Note: This post contains language of a sensitive and adult nature. True Christian™ ladies, please have your fathers or husbands read it for you, assuming you need to know at all, which you most likely don't.
I praise God for the human prostate. God intelligently designed the urethra in men to go through the prostate, whereas in some mere beasts, the urethra goes around the prostate (
almost-True Christian™ source). This means that in human males, swelling of the prostate can cause difficulty with urination, thus giving the Lord an entertaining way of smiting sinners.
Also, a certain act that the Lord hates stimulates the prostate. This causes homers to enjoy their deathstyle choice and thus makes it easier for the Lord to infect them with GRID and then damn them.